By Jennifer I. Lim
This reference showcases exudative and nonexudative AMD remedy ideas utilizing argon and diode lasers, submacular and macular translocation surgical procedure, photodynamic treatment, radiation, feeder vessel remedy, thermotherapy, and antiangiogenesis medicines. together with a hundred and sixty colour illustrations, Age-Related Macular Degeneration will gain medical ophthalmologists, pathologists, physiologists, and pharmacologists; optometrists; cellphone and molecular biologists and biochemists; retinal experts; AMD researchers; and graduate and clinical college scholars in those disciplines.
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Extra resources for Age-Related Macular Degeneration
6. Curcio CA, Millican CL. Basal linear deposit and large drusen are specific for early age-related maculopathy. Arch Ophthalmol 1999;117:329–339. 7. Sarks JP, Sarks SH, Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye 1988;2:552–577. 8. Bressler NM, Silva JC, Bressler SB, Fine SL, Green WR. Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration. Retina 1994;14:130–142. 9. van der Schaft TL, de Bruijn WC, Mooy CM, de Jong PT.
Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP. Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study. Br J Ophthalmol 1999;83:358–368. 3. Green WR, Enger C. Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture. Ophthalmology 1993;100:1519–1535. 4. Spraul CW, Grossnildaus HE. Characteristics of Drusen and Bruch’s membrane in postmortem eyes with age-related macular degeneration. Arch Ophthalmol 1997;115:267–273.
Gass (21) has suggested two types of CNVM: Type I, common in AMD, grows under the RPE, while type 11, seen in other pathologies such as the presumed ocular histoplasmosis syndrome (POHS), grows under the neurosensory retina (Fig. 8,9). Gass postulated that, since there is a generalized weakening of normal adhesion between the RPE and Bruch’s membrane in AMD, the proliferating choroidal vessels are growing unimpeded in the sub-RPE space. In contrast, POHS includes only focal defects in the RPE–Bruch’s membrane integrity, and therefore, the vascular proliferation cannot easily grow under the RPE.